1. What is HCG Percent Change?

The HCG percent change calculation measures the rate of change in human chorionic gonadotropin levels between two time points. This is crucial for monitoring pregnancy progression, evaluating ectopic pregnancy risk, and assessing miscarriage likelihood.

2. How Does the Calculator Work?

The calculator uses the percent change formula:

Where:

• \( hCG_1 \) — Initial hCG measurement (mIU/mL)
• \( hCG_2 \) — Follow-up hCG measurement (mIU/mL)

Explanation: This formula calculates the percentage increase or decrease in hCG levels between two measurements, providing insight into pregnancy viability and development.

3. Importance of HCG Monitoring

Details: Serial hCG measurements are essential for evaluating early pregnancy health. In viable intrauterine pregnancies, hCG typically doubles every 48-72 hours during the first trimester. Abnormal patterns may indicate ectopic pregnancy or miscarriage.

4. Using the Calculator

Tips: Enter both hCG values in mIU/mL. Ensure measurements are taken at appropriate intervals (usually 48 hours apart). Initial hCG must be greater than zero for calculation.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal hCG percent increase?
A: In viable pregnancies, hCG typically increases by 35% or more over 48 hours. A 66% or greater increase is often considered optimal.

Q2: When should I be concerned about hCG changes?
A: Concern arises with less than 35% increase over 48 hours, plateauing levels, or decreasing levels, which may indicate non-viable pregnancy.

Q3: How often should hCG levels be measured?
A: Typically every 48-72 hours in early pregnancy when monitoring is clinically indicated. Follow your healthcare provider's recommendations.

Q4: Can hCG percent change diagnose ectopic pregnancy?
A: While abnormal rise patterns may suggest ectopic pregnancy, diagnosis requires ultrasound and clinical evaluation. Slow rise alone is not diagnostic.

Q5: What factors affect hCG levels?
A: Gestational age, multiple gestation, laboratory assay variations, and individual biological differences can all influence hCG measurements.